The ferumoxytol in renal insufficiency study (FiRST)
نویسندگان
چکیده
Background Imaging in patients with renal insufficiency (RI) is limited by contrast induced nephropathy and nephrogenic systemic fibrosis. Ferumoxytol is an FDA approved superparamagnetic iron compound used for the treatment of anemia in patients with renal insufficiency. Previous studies of its use as an MRA contrast agent did not assess safety, were not conducted in patients with RI, and were limited by small sample size. We characterized the safety, image quality, and clinical impact of ferumoxytol-enhanced MRA (FeMRA) in patients with RI as compared to gadoliniumenhanced MRA (GeMRA) in patients without RI.
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عنوان ژورنال:
دوره 15 شماره
صفحات -
تاریخ انتشار 2013